Dr. Wheeler's Publications

Papers

Zetterström, T., Wheeler, D.B., Boutelle, M.G. and Fillenz, M. (1991). Striatal ascorbate and its relationship to dopamine receptor stimulation and motor activity. Eur. J. Neurosci. 3(10):940-946.

Wheeler, D.B., Randall, A. and Tsien, R.W. (1994). Roles of N-type and Q-type Ca²⁺ channels in supporting hippocampal synaptic transmission. Science 264:107-111.

Wheeler, D.B., Tsien, R.W. and Randall, A. (1994). Identification of calcium channels that control neurosecretion. Science 266:830-831.

Wheeler, D., Boutelle, M.G. and Fillenz, M. (1995). The role of N-methyl-D-aspartate receptors in the regulation of physiologically released dopamine. Neuroscience 65:767-774.

Wheeler, D.B., Randall, A. and Tsien, R.W. (1996). Changes in action potential duration alter reliance of excitatory synaptic transmission on multiple types of Ca²⁺ channels in rat hippocampus. J. Neurosci. 16:2226-2237.

Donohoe, M.T., Kravitz, R.L., Wheeler, D.B., Chandra, R., Chen, A. and Humphries, N. (1999) Reasons for outpatient referrals from generalists to specialists. J. Gen. Intern. Med. 14(5):281-286.

Jun, K., Smith, S.M., Piedras-Renteria, E., Wheeler, D.B., Lee, S.B., Lee, T.G., Scheller, R.H., Tsien, R.W. and Shin, H.-S. (1999). Ablation of P/Q-type calcium channels currents and progressive, fatal ataxia in mice lacking the a_1A subunit. Proc. Natl. Acad. Sci. U.S.A. 96(26):15245-15250.

Chapters & Reviews

Wheeler, D.B., Sather, W.A., Randall, A. and Tsien, R.W. (1994). Distinctive properties of a neuronal calcium channel and its contribution to excitatory transmission in the CNS. Adv. Second Messenger Phosphoprotein Res. 29, Molecular and Cellular Mechanisms of Neurotransmitter Release. L. Stjärne, P. Greengard, S. Grillner, T. Hökfelt and D. Ottoson (Eds.), Raven Press, New York. pp. 155-172.

Wheeler, D.B., Randall, A., Sather, W.A. and Tsien, R.W. (1995). Neuronal calcium channels encoded by the a_1A subunit and their contribution to excitatory synaptic transmission in the CNS. Prog. Brain Res. 105, Gene Expression in the Central Nervous System. A.C.H. Yu, L.F. Eng, K.J. McMahan, H. Schulman and A. Stadlin (Eds.), Elsevier Science BV, Amsterdam. pp. 65-78.

Tsien, R.W. and Wheeler, D.B. (1999). Voltage-gated calcium channels. In: Calcium as a Cellular Regulator. E. Carafoli and C.B. Klee (Eds.), Oxford University Press, New York. pp 171-199.

Bergsman, J.B., Wheeler, D.B. and Tsien, R.W. (2000). Classification and function of voltage-gated calcium channels. In: Pharmacology of Ionic Channel Function: Activators and Inhibitors (Handbook of Experimental Pharmacology, Volume 147). M. Endo, Y. Kurachi and M. Mishina (Eds.), Springer-Verlag, Heidelberg. pp 55-83.

Abstracts

Boutelle, M.G., Wheeler, D.B. and Fillenz, M. (1990). Effects of ketamine on basal and tail pinch-stimulated levels of extracellular brain ascorbic acid. Eur. J. Pharmacol. 183(3):965- 966.

Wheeler, D.B., Boutelle, M.G., Zetterström, T. and Fillenz, M. (1990). Effects of apomorphine on extracellular brain ascorbic acid. Eur. J. Pharmacol. 183(2):431.

Fillenz, M., Wheeler, D.B. and Boutelle, M.G. (1991). Regulation of the physiological release of dopamine. In: Monitoring Molecules in Neuroscience. Proceedings of the Fifth International Congress on In Vivo Methods. H. Rollema, B. Westerink and W. J. Drifthout, eds. University Centre for Pharmacy, Gröningen, Noordwikjkerhaut, pp. 315-316.

Wheeler, D.B. and Fillenz, M. (1991). Local N-methyl-D-aspartate receptors modulate basal and tail pinch-stimulated release of dopamine in rat striatum. Eur. J. Neurosci. 3(Suppl. 4):167.

Malgaroli, A., Wheeler, D.B., Naldi, E., Ciardo, A., Bergamaschi, A. and Tsien, R.W. (1993). A presynaptic alteration supporting LTP in hippocampal neurons: contrast with effect of a-latrotoxin. Soc. Neurosci. Abstr. 19(2):911.

Randall, A.D., Wheeler, D.B. and Tsien, R.W. (1993). Modulation of Q-type Ca²⁺ channels and Q-type Ca²⁺ channel-mediated synaptic transmission by metabotropic and other G-protein linked receptors. Funct. Neurol. 8(Suppl. 4):44-45.

Wheeler, D.B. Tsien, R.W. and Randall, A.D. (1993). A calcium channel with novel pharmacology supports synaptic transmission and plasticity in the hippocampus. Soc. Neurosci. Abstr. 19(2):909.

Wheeler, D.B., Randall, A.D. and Tsien, R.W. (1994). The basis of concerted actions of multiple Ca²⁺ channel types in excitatory synaptic transmission in area CA1 of rat hippocampal slice in vitro. J. Physiol. 403P:30.

Wheeler, D.B., Randall, A. and Tsien, R.W. (1995). Concerted actions of multiple Ca²⁺ channel types in excitatory synaptic transmission. Soc. Neurosci. Abstr. 21(3):1754.

Wheeler, D.B. and Tsien, R.W. (1996). Mechanisms of long-term potentiation induced by elevated extracellular calcium. Soc. Neurosci. Abstr. 22(2):1509.

Jun, K., Smith, S.M., Piedras-Renteria, E., Wheeler, D.B., Lee, S.B., Scheller, R.H., Tsien, R.W. and Shin, H.-S. (1999). Knockout of the Ca²⁺ channel a_1A subunit ablates P- and Q-type currents and causes generalized dystonia. Soc. Neurosci. Abstr. 25(1):195.

Mermelstein, P.G., Graef, I.A., Pitt, G.S., Wheeler, D.B., Dasgupta, N., Mukai, T., Crabtree, G.R. and Tsien, R.W. (1999). Calcineurin and GSK-3b regulate NF-Atc4-dependent gene transcription in hippocampal neurons. Soc. Neurosci. Abstr. 25(1):469.